An enantioselective synthesis of the C(33)-C(37) fragment of Amphotericin B.
نویسندگان
چکیده
An enantioselective synthesis of the C(33)-C(37) tripropionate fragment of Amphotericin B has been developed in only 6 steps.
منابع مشابه
Model studies on a diastereoselective synthesis of the C(33)–C(37) fragment of Amphotericin B
A new, short and highly diastereoselective synthetic route aiming at the C(33)–C(37) fragment of Amphotericin B has been developed. Studies with a model aldehyde (benzaldehyde) have given very promising results: the desired stereochemistry of all four stereocenters of the target molecule has been achieved with high diastereoselection. The stereochemistry of three key intermediates and the targe...
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 1 18 شماره
صفحات -
تاریخ انتشار 2003